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Dasatinib metabolite M6
$300 – $2,350
Products Details
Product Description
– Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative metabolite of Dasatinib (HY-10181). Dasatinib is a potent and orally active dual Bcr-Abl and Src family tyrosine kinase inhibitor[1].
Web ID
– HY-131669
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C22H24ClN7O3S
References
– [1]Lisa J Christopher, et al. Biotransformation of [14C]dasatinib: in vitro studies in rat, monkey, and human and disposition after administration to rats and monkeys. Drug Metab Dispos. 2008 Jul;36(7):1341-56.
CAS Number
– 910297-53-9
Molecular Weight
– 501.99
Compound Purity
– 99.23
SMILES
– O=C(O)CN1CCN(C2=NC(C)=NC(NC3=NC=C(C(NC4=C(C)C=CC=C4Cl)=O)S3)=C2)CC1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Drug Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
