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Dapsone hydroxylamine
SKU
HY-137155-10 mg
Category Reference compound
Tags Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB, Inflammation/Immunology, Reactive Oxygen Species
$330 – $480
Products Details
Product Description
– Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity[1].
Web ID
– HY-137155
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C12H12N2O3S
References
– [1]Wozel G, et al. Dapsone hydroxylamine inhibits the LTB4-induced chemotaxis of polymorphonuclear leukocytes into human skin: results of a pilot study. Inflamm Res. 1997 Oct;46(10):420-2.|[2]Albuquerque RV, et al. In Vitro Protective Effect and Antioxidant Mechanism of Resveratrol Induced by Dapsone Hydroxylamine in Human Cells. PLoS One. 2015 Aug 18;10(8):e0134768.
CAS Number
– 32695-27-5
Molecular Weight
– 264.30
SMILES
– O=S(C1=CC=C(C=C1)N)(C2=CC=C(C=C2)NO)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Reactive Oxygen Species
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Product type
– Reference compound
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