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Danirixin
$100 – $1,750
Products Details
Product Description
– Danirixin is a selective, and reversible CXCR2 antagonist, with IC50 of 12.5 nM for CXCL8.
Web ID
– HY-19768
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H21ClFN3O4S
References
– [1]Miller BE, et al. The pharmacokinetics and pharmacodynamics of danirixin (GSK1325756)–a selective CXCR2 antagonist?–in healthy adult subjects. BMC Pharmacol Toxicol. 2015 Jun 20;16:18.
CAS Number
– 954126-98-8
Molecular Weight
– 441.90
Compound Purity
– 98.45
SMILES
– O=C(NC1=CC=C(Cl)C(S([C@H]2CCCNC2)(=O)=O)=C1O)NC3=C(C)C(F)=CC=C3
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology; Endocrinology
Solubility
– DMSO : 8 mg/mL (ultrasonic;warming)
Target
– CXCR
Isoform
– CXCR2
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
