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Damnacanthol
$430 – $1,300
Products Details
Product Description
– Damnacanthol is a natural product that can be isolated from Damnacanthus major[1]. Damnacanthol has anti-15-lipoxygenase activity and can inhibit nitric oxide production in LPS-activated macrophages RAW 264.7 cells[2].
Web ID
– HY-N11058
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H12O5
References
– [1]Ayyangar N R, et al. Anthraquinone and anthrone series—XXIII: The non-identity of 1: 3: 8-trihydroxy-2-hydroxymethyl-anthraquinone with versicolorin and a synthesis of damnacanthol and damnacanthal. Tetrahedron, 1959, 6(4): 331-337.|[2]Dzoyem JP, et al. Inhibition of Nitric Oxide Production in LPS-Stimulated RAW 264.7 Macrophages and 15-LOX Activity by Anthraquinones from Pentas schimperi. Planta Med. 2016 Sep;82(14):1246-51.
CAS Number
– 477-83-8
Molecular Weight
– 284.26
Compound Purity
– 99.76
SMILES
– O=C1C2=C(C=CC=C2)C(C3=CC(O)=C(CO)C(OC)=C13)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Lipoxygenase;NO Synthase
Isoform
– 15-LOX
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
