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Dalbavancin (hydrochloride)
$150 – $1,250
Products Details
Product Description
– Dalbavancin hydrochloride (MDL-63397 hydrochloride) is a semisynthetic lipoglycopeptide antibiotic with potent bactericidal activity against Gram-positive bacteria. Dalbavancin hydrochloride inhibits Staphylococcus aureus and Bacillus anthracis with MIC90s of 0.06 μg/mL and 0.25 μg/mL, respectively[1][2].
Web ID
– HY-17586
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C88H101Cl3N10O28
Citations
– Antivir Res. 2020 Jun;178:104786.|Cell Res. 2021 Jan;31(1):17-24.|The Journal of Antibiotics . 2019 Feb;72(2):114-117.|Cell Res. 2021 Jan;31(1):17-24.|Enferm Infec Micr Cl. 30 July 2022.|Eur J Orthop Surg Traumatol. 2023 Jun 4.|Sci Rep. 2022 Sep 26;12(1):16001.
References
– [1]Heine HS, et al. Activity of dalbavancin against Bacillus anthracis in vitro and in a mouse inhalation anthrax model. Antimicrob Agents Chemother. 2010 Mar;54(3):991-6.|[2]Bennett JW, et al. Dalbavancin in the treatment of complicated skin and soft-tissue infections: a review. Ther Clin Risk Manag. 2008 Feb;4(1):31-40.
CAS Number
– 2227366-51-8
Molecular Weight
– 1853.15
Compound Purity
– 99.50
SMILES
– O[C@@H]([C@@H](O)[C@@H]1O)[C@H](O[C@@H]1CO)OC2=C(C3=CC([C@@](C4=O)([H])NC([C@@](NC([C@](NC([C@@](NC5=O)([H])C6)=O)([H])C(C=C7OC(C=C8[C@H]5NC)=C(C=C8)O)=C(C(O)=C7)Cl)=O)([H])C9=CC%10=C(O[C@H](O[C@H](C(O)=O)[C@@H](O)[C@@H]%11O)[C@@H]%11NC(CCCCCCCCC(C)C)=O)C(OC%12=CC=C6C=C%12)=C9)=O)=CC=C3O)C([C@@](NC([C@](N4)([H])[C@@H](C%13=CC=C(O%10)C(Cl)=C%13)O)=O)([H])C(NCCCN(C)C)=O)=CC(O)=C2.[H]Cl
Clinical Information
– Launched
Research Area
– Infection
Solubility
– DMSO : 250 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial
Isoform
– Glycopeptide
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
