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Dacarbazine (hydrochloride)
Products Details
Product Description
– Dacarbazine hydrochloride is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine hydrochloride inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine hydrochloride can be used for the research of metastatic malignant melanoma[1][2].
Web ID
– HY-B0078B
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C6H11ClN6O
References
– [1]Rojo JM, et al. Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio. Chemotherapy. 1983;29(5):345-51.|[2]Al-Badr AA, et al. Dacarbazine. Profiles Drug Subst Excip Relat Methodol. 2016;41:323-77.
CAS Number
– 17925-90-5
Molecular Weight
– 218.64
SMILES
– O=C(C1=C(/N=N/N(C)C)NC=N1)N.[H]Cl
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Antibiotic
Pathway
– Anti-infection
Product type
– Reference compound
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