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Products Details
Product Description
– Dacarbazine citrate is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine citrate inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine Citrate can be used for the research of apoptosis and various cancers such as metastatic malignant melanoma[1][2].
Web ID
– HY-B0078A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C12H18N6O8
References
– [1]Abdullah A Al-Badr, et al. Dacarbazine. Profiles Drug Subst Excip Relat Methodol|[2]J M Rojo, et al. Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio. Chemotherapy. 1983;29(5):345-51.|[3]Int J Cancer, et al. Dacarbazine alone or associated with melanoma-bearing cancer pain model induces painful hypersensitivity by TRPA1 activation in mice. Int J Cancer. 2020 May 15;146(10):2797-2809.
CAS Number
– 64038-56-8
Molecular Weight
– 374.31
SMILES
– O=C(C1=C(/N=N/N(C)C)NC=N1)N.O=C(CC(C(O)=O)(O)CC(O)=O)O
Clinical Information
– Launched
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis
Pathway
– Anti-infection;Apoptosis
Product type
– Reference compound
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