Dabuzalgron

$155$280

Products Details

Product Description

– Dabuzalgron (Ro 115-1240) is an orally active and selective α-1A adrenergic receptor agonist for the treatment of urinary incontinence. Dabuzalgron protects against Doxorubicin-induced cardiotoxicity by preserving mitochondrial function[1].

Web ID

– HY-117071

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C12H16ClN3O3S

References

– [1]Beak J, et al. An Oral Selective Alpha-1A Adrenergic Receptor Agonist Prevents Doxorubicin Cardiotoxicity. JACC Basic Transl Sci. 2017 Feb;2(1):39-53.

CAS Number

– 219311-44-1

Molecular Weight

– 317.79

Compound Purity

– 98.72

SMILES

– CS(=O)(NC1=C(Cl)C=CC(OCC2=NCCN2)=C1C)=O

Clinical Information

– No Development Reported

Research Area

– Endocrinology; Cardiovascular Disease

Solubility

– DMSO : 26 mg/mL (ultrasonic)

Target

– Adrenergic Receptor;Apoptosis

Isoform

– α adrenergic receptor

Pathway

– Apoptosis;GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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