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Products Details
Product Description
– D6808 is a highly selective and potent c‑Met inhibitor with an IC50 value of 2.9 nM. D6808 induces cell apoptosis and cell cycle arrest. D6808 can be used for the research of NSCLC and gastric cancers[1].
Web ID
– HY-151905
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C30H25F3N6O2
References
– [1]Wang C, et al. Discovery of D6808, a Highly Selective and Potent Macrocyclic c-Met Inhibitor for Gastric Cancer Harboring MET Gene Alteration Treatment. J Med Chem. 2022 Nov 24;65(22):15140-15164.
Molecular Weight
– 558.55
SMILES
– O=C1NCCCCN2C=C(C3=CN=C4C=CC(CCN5N=C(C6=CC(C(F)(F)F)=C1C=C6)C=CC5=O)=CC4=C3)C=N2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Met/HGFR
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
