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Products Details
Product Description
– D5261 is a potent, type III allosteric tropomyosin-related kinase A (TrkA) inhibitor[1].
Web ID
– HY-144690
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H29N5O3
References
– [1]Jing Guo, et al. Discovery of novel TrkA allosteric inhibitors: Structure-based virtual screening, biological evaluation and preliminary SAR studies. Eur J Med Chem. 2022 Jan 15;228:114022.
CAS Number
– 1574574-57-4
Molecular Weight
– 447.53
SMILES
– CC1=C(C=C(C=C1)C(NC2=CN=C(C=C2)N3CCN(C3=O)C4CCCC4)=O)N5CCCC5=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Trk Receptor
Isoform
– TrkA
Pathway
– Neuronal Signaling;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
