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D1R antagonist 1

Products Details

Product Description

– D1R antagonist 1 (compound 12a) is a D1R antagonist, involved in G-protein- and β-arrestin-based signaling[1].

Web ID

– HY-149336

Shipping

– Room temperature

Molecular Formula

– C22H26BrNO4

References

– [1]Namballa HK, et al. Discovery of Selective Dopamine Receptor Ligands Derived from (-)-Stepholidine via C-3 Alkoxylation and C-3/C-9 Dialkoxylation. J Med Chem. 2023 Jul 27;66(14):10060-10079.

Molecular Weight

– 448.35

SMILES

– OC1=C(C=C(C2=C1)CCN3[C@H]2CC4=C(C=C(C(OCC)=C4C3)O)Br)OCCC

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Dopamine Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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