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D-Tetrahydropalmatine
$56 – $343
Products Details
Product Description
– D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis[1]. D-Tetrahydropalmatine is a dopamine (DA) receptor antagonist with preferential affinity toward the D1 receptors[2]. D-Tetrahydropalmatine is a potent organic cation transporter 1 (OCT1) inhibitor[3].
Web ID
– HY-N2003
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C21H25NO4
References
– [1]Ma ZJ, et al. [Effects of different types and standard of processing vinegaron inherent constituents in rhizoma of Corydalis yanhusuo]. Zhongguo Zhong Yao Za Zhi. 2006 Mar;31(6):465-7.|[2]Xu SX, et al. Effects of tetrahydroprotoberberines on dopamine receptor subtypes in brain. Zhongguo Yao Li Xue Bao. 1989 Mar;10(2):104-10.|[3]Tu M, et al. Organic cation transporter 1 mediates the uptake of monocrotaline and plays an important rolein its hepatotoxicity. Toxicology. 2013 Sep 15;311(3):225-30.
CAS Number
– 3520-14-7
Molecular Weight
– 355.43
Compound Purity
– 99.97
SMILES
– COC1=CC=C2C(CN3CCC4=CC(OC)=C(OC)C=C4[C@@]3([H])C2)=C1OC
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– Dopamine Receptor
Isoform
– D1 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Natural Products
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