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D-Cl-amidine
SKU
HY-100574C-Get quote
Category Reference compound
Tags Apoptosis;Epigenetics, Apoptosis;Protein Arginine Deiminase, Cancer; Inflammation/Immunology
Products Details
Product Description
– D-Cl-amidine is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].
Web ID
– HY-100574C
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C14H19ClN4O2
References
– [1]Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3(12):1081-1085.
CAS Number
– 1404060-15-6
Molecular Weight
– 310.78
SMILES
– O=C(N[C@@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Protein Arginine Deiminase
Pathway
– Apoptosis;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.