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D-Alanine
SKU
HY-41700-10mM/1mL
Category Natural Products
Tags Endogenous Metabolite, Metabolic Enzyme/Protease, Neurological Disease
$50 – $60
Products Details
Product Description
– D-Alanine is a weak GlyR (inhibitory glycine receptor) and PMBA agonist, with an EC50 of 9 mM for GlyR[1][2].
Web ID
– HY-41700
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C3H7NO2
References
– [1]Schmieden V, et al. Pharmacology of the inhibitory glycine receptor: agonist and antagonist actions of amino acids and piperidine carboxylic acid compounds. Mol Pharmacol. 1995 Nov;48(5):919-27.|[2]Saitoh T, et al. A novel antagonist, phenylbenzene omega-phosphono-alpha-amino acid, for strychnine-sensitive glycine receptors in the rat spinal cord. Br J Pharmacol. 1994 Sep;113(1):165-70.|[3]Mao Horio, et al. Effects of D-Amino Acid Oxidase Inhibitor on the Extracellular D-Alanine Levels and the Efficacy of D-Alanine on Dizocilpine-Induced Prepulse Inhibition Deficits in Mice. The Open Clinical Chemistry Journal, 2009, 2: 16-21
CAS Number
– 338-69-2
Molecular Weight
– 89.09
Compound Purity
– 98.0
SMILES
– N[C@@H](C(O)=O)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : < 1 mg/mL (ultrasonic;warming;heat to 80°C)|H2O : 120 mg/mL (ultrasonic)
Target
– Endogenous Metabolite
Isoform
– Human Endogenous Metabolite;Microbial Metabolite
Pathway
– Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.