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Products Details
Product Description
– Cyprodinil-13C6 is the 13C6 labeled Cyprodinil. Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).
Web ID
– HY-116214S1
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C8 13C6H15N3
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800.|[3]Masner, P., et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pestic. Sci. 42(3),163-166 (1994).
CAS Number
– 1773496-63-1
Molecular Weight
– 231.24
SMILES
– CC1=CC(C2CC2)=NC(N[13C]3=[13CH][13CH]=[13CH][13CH]=[13C]3[H])=N1
Clinical Information
– No Development Reported
Research Area
– Infection; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Androgen Receptor;Fungal;Isotope-Labeled Compounds
Pathway
– Anti-infection;Others;Vitamin D Related/Nuclear Receptor
Product type
– Isotope-Labeled Compounds
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