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Products Details
Product Description
– CypD-IN-3 is a potent and subtype-selective cyclophilin D (CypD) inhibitor. CypD-IN-3 has CypD affinity with an IC50 value of 0.01 μM. CypD-IN-3 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging, autophagy and diabetes[1].
Web ID
– HY-151487
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C53H61N7O11
References
– [1]Alexander A Peterson, et al. Discovery and molecular basis of subtype-selective cyclophilin inhibitors. Nat Chem Biol. 2022 Sep 26.
CAS Number
– 2651994-75-9
Molecular Weight
– 972.09
SMILES
– NCCOCCNC([C@@H]1CCNC(/C=C/C(N2CCC[C@](C2)(C(N[C@H](C(NCC3=C(CC(N1)=O)C=CC=C3)=O)CC4=CC=C(C=C4)C5=CC=C(C=C5)CC(C(O)=O)C(O)=O)=O)CC6=CC=CC=C6)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Sirtuin
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
