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Products Details
Product Description
– CYP3A4-IN-1 (compound 5a) is a potent cytochrome P450 3A4 (CYP3A4) inhibitor with an IC50 value of 0.085 µM[1].
Web ID
– HY-150574
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C31H37N5O3S
References
– [1]Samuels ER, et al. An increase in side-group hydrophobicity largely improves the potency of ritonavir-like inhibitors of CYP3A4. Bioorg Med Chem. 2020 Mar 15;28(6):115349.
CAS Number
– 2771297-34-6
Molecular Weight
– 559.72
SMILES
– O=C(NCC1=CN=CC=C1)C(NC2=CC=CC=C2)CSC[C@H](NC(OC(C)(C)C)=O)CC3=CNC4=CC=CC=C34
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Cytochrome P450
Isoform
– CYP3
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
