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Cycloguanil (hydrochloride)
$47 – $825
Products Details
Product Description
– Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].
Web ID
– HY-12784A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C11H15Cl2N5
References
– [1]Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200.
CAS Number
– 152-53-4
Molecular Weight
– 288.18
Compound Purity
– 99.91
SMILES
– NC1=NC(N)=NC(C)(N1C2=CC=C(C=C2)Cl)C.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)|H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Drug Metabolite;Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
