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Products Details
Product Description
– Cycloguanil, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes[1].
Web ID
– HY-12784
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C11H14ClN5
References
– [1]Matthaei J, et al. OCT1 Deficiency Affects Hepatocellular Concentrations and Pharmacokinetics of Cycloguanil, the Active Metabolite of the Antimalarial Drug Proguanil. Clin Pharmacol Ther. 2019 Jan;105(1):190-200.
CAS Number
– 516-21-2
Molecular Weight
– 251.72
SMILES
– NC1=NC(N)=NC(C)(C)N1C2=CC=C(Cl)C=C2
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Drug Metabolite;Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
