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CYC-116
$92 – $640
Products Details
Product Description
– CYC-116 is a potent aurora A and aurora B inhibitor with Kis of 8 and 9 nM, respectively.
Web ID
– HY-10558
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C18H20N6OS
References
– [1]Wang S, et al. Discovery of N-phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors. J Med Chem. 2010 Jun 10;53(11):4367-78.
CAS Number
– 693228-63-6
Molecular Weight
– 368.46
Compound Purity
– 98.17
SMILES
– CC1=C(SC(N)=N1)C2=NC(NC3=CC=C(C=C3)N4CCOCC4)=NC=C2
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 15 mg/mL (ultrasonic)|H2O : 1 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– Aurora Kinase
Isoform
– Aurora A;Aurora B
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
