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Products Details
Product Description
– CXCR4 modulator-2 (compound Z7R) is a highly potent CXCR4 modulator with an IC50 value of 1.25 nM. CXCR4 modulator-2 has acceptable stability (t1/2 = 77.1 min) in mouse serum and exhibits anti-inflammatory activity in mouse edema model[1].
Web ID
– HY-146054
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H32N8O2
References
– [1]Oum YH, et al. Discovery of novel aminopiperidinyl amide CXCR4 modulators through virtual screening and rational drug design. Eur J Med Chem. 2020;201:112479.
CAS Number
– 2488943-55-9
Molecular Weight
– 428.53
SMILES
– O=C(NC1CCN(C(CCN2C=CC3=C2C=NC=C3)=O)CC1)[C@H](N)CCCNC(N)=N
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CXCR
Isoform
– CXCR4
Pathway
– GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
