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Products Details
Product Description
– CXCR4-IN-2 (compound A1) is a bifunctional fluorinated small molecule that is a potent CXCR4 inhibitor with anticancer activity. CXCR4-IN-2 has cytotoxic (IC50: 60 μg/mL; 72 h) and antiproliferative effects on mouse colorectal cancer (CRC) cells. CXCR4-IN-2 induces cell arrest in the G2/M phase and induces apoptosis[1].
Web ID
– HY-149558
Shipping
– Room temperature
Molecular Formula
– C21H20F6N4S
References
– [1]Khorramdelazad H, et al. Antitumor activities of a novel fluorinated small molecule (A1) in CT26 colorectal cancer cells: molecular docking and in vitro studies. J Biomol Struct Dyn. 2023 Sep 13:1-14.. .
Molecular Weight
– 474.47
SMILES
– CC1=CC=C(/N=C(NC(N/C(C(F)(F)F)=N/C2=CC(C)=C(C)C=C2)=S)C(F)(F)F)C=C1C
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;CXCR
Pathway
– Apoptosis;GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
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