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CX546
SKU
HY-12505-10 mg
Category Reference compound
Tags Autophagy;iGluR, Autophagy;Membrane Transporter/Ion Channel;Neuronal Signaling, Neurological Disease
$75 – $455
Products Details
Product Description
– CX546 is a first-generation and selective benzamide-type positive AMPAR modulator. CX546 is a prototypical ampakine agent and has antipsychotic effects[1][2].
Web ID
– HY-12505
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C14H17NO3
References
– [1]Lauterborn JC, et al. Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons. J Neurosci. 2000 Jan 1;20(1):8-21.|[2]Lipina T, et al. The ampakine CX546 restores the prepulse inhibition and latent inhibition deficits in mGluR5-deficient mice. Neuropsychopharmacology. 2007 Apr;32(4):745-56.
CAS Number
– 215923-54-9
Molecular Weight
– 247.29
Compound Purity
– 99.38
SMILES
– O=C(N1CCCCC1)C2=CC=C(OCCO3)C3=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)|Ethanol : 100 mg/mL (ultrasonic)|H2O : 2 mg/mL (ultrasonic)
Target
– Autophagy;iGluR
Isoform
– AMPA Receptor
Pathway
– Autophagy;Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.