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Products Details
Product Description
– CWI1-2 hydrochloride is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1].
Web ID
– HY-153274A
Shipping
– Room temperature
Molecular Formula
– C22H18Cl4N6O3
References
– [1]Hengyou Weng, et al. The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia. Cancer Cell. 2022 Dec 12;40(12):1566-1582.e10.
CAS Number
– 2408590-37-2
Molecular Weight
– 556.23
SMILES
– OC(C=C1)=C(C=C1Cl)/C=N/N=C(N/N=CC(C=C2Cl)=C(C=C2)O)N/N=C/C(C=C3Cl)=C(C=C3)O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
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