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CWI1-2
$130 – $1,250
Products Details
Product Description
– CWI1-2 is an IGF2BP2 inhibitor that binds IGF2BP2 and inhibits its interaction with m6A-modified target transcripts, induces apoptosis and differentiation, and shows promising anti-leukemic effects[1].
Web ID
– HY-153274
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C22H17Cl3N6O3
References
– [1]Hengyou Weng, et al. The m6A reader IGF2BP2 regulates glutamine metabolism and represents a therapeutic target in acute myeloid leukemia. Cancer Cell. 2022 Dec 12;40(12):1566-1582.e10.
CAS Number
– 2408590-36-1
Molecular Weight
– 519.77
Compound Purity
– 98.00
SMILES
– OC(C=C1)=C(C=C1Cl)/C=N/N=C(N/N=CC(C=C2Cl)=C(C=C2)O)N/N=C/C(C=C3Cl)=C(C=C3)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Apoptosis
Pathway
– Apoptosis
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
