CWHM-1008

SKU HY-111746-10 mg Category Tags , ,

$350$2,650

Products Details

Product Description

– CWHM-1008 is a potent and orally active antimalarial agent, with EC50 values of 46 and 21 nM against agent-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains, respectively[1].

Web ID

– HY-111746

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C22H26F3N3O

References

– [1]Meyers MJ, et al. 4-Aryl Pyrrolidines as a Novel Class of Orally Efficacious Antimalarial Agents. Part 1: Evaluation of 4-Aryl- N-benzylpyrrolidine-3-carboxamides. J Med Chem. 2019 Mar 22.

CAS Number

– 2362539-97-5

Molecular Weight

– 405.46

Compound Purity

– 99.06

SMILES

– C[C@H](NC([C@H]1CNC[C@@H]1C2=CC=C(C(F)(F)F)C=C2)=O)C3=CC=C(N(C)C)C=C3

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– DMSO : 250 mg/mL (ultrasonic)

Target

– Parasite

Isoform

– Plasmodium

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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