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CVT-10216
$125 – $688
Products Details
Product Description
– CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects[1].
Web ID
– HY-19801
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C24H19NO7S
References
– [1]Overstreet DH, et al. A selective ALDH-2 inhibitor reduces anxiety in rats.Pharmacol Biochem Behav. 2009 Dec;94(2):255-61.
CAS Number
– 1005334-57-5
Molecular Weight
– 465.48
Compound Purity
– 99.0
SMILES
– O=C(O)C1=CC=CC(COC2=CC=C3C(C(C4=CC=C(NS(=O)(C)=O)C=C4)=COC3=C2)=O)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMF : 25 mg/mL (ultrasonic;warming)|DMSO : 20 mg/mL (ultrasonic;warming)
Target
– Aldehyde Dehydrogenase (ALDH)
Isoform
– ALDH2
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
