CVN636

$350$7,200

Products Details

Product Description

– CVN636 is a potent, orally active and selective mGluR7 allosteric agonist with an EC50 value of 7 nM for hu mGluR7. CVN636 has central nervous system (CNS) permeability[1].

Web ID

– HY-153615

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C19H20FNO4S

References

– [1]Dickson L, et, al. Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist. ACS Med Chem Lett. 2023 Mar 2;14(4):442-449.|[2]Ayscough AP, et, al. Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist. ACS Med Chem Lett. 2023 Mar 2;14(4):442-449.

CAS Number

– 2226732-62-1

Molecular Weight

– 377.43

Compound Purity

– 99.47

SMILES

– CS(=O)([C@H]1C2=CC=CC=C2OC[C@@H]1NC([C@H](C3=CC=C(C=C3)F)C)=O)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– mGluR

Isoform

– mGluR7

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

My Cart
Close Wishlist
Close Recently Viewed
Categories

Please fill out this form to request the file. We will send it to your Email address shortly. Thanks.

Please enable JavaScript in your browser to complete this form.

=

Please fill out this form to request the pricing.
We will send it to your email address shortly.
Thanks.

Please enable JavaScript in your browser to complete this form.

=