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CU-CPT-8m
SKU
HY-112050-1 mg
Category Reference compound
Tags Immunology/Inflammation, Inflammation/Immunology, Toll-like Receptor (TLR)
$62 – $1,210
Products Details
Product Description
– CU-CPT-8m is a specific TLR8 antagonist, with an IC50 of 67 nM.
Web ID
– HY-112050
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H12N4O
References
– [1]Zhang S, et al. Small-molecule inhibition of TLR8 through stabilization of its resting state. Nat Chem Biol. 2018 Jan;14(1):58-64.
CAS Number
– 125079-83-6
Molecular Weight
– 252.27
Compound Purity
– 99.98
SMILES
– O=C(C1=C2N=CC=C(C3=CC=CC(C)=C3)N2N=C1)N
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Toll-like Receptor (TLR)
Isoform
– TLR8
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.