![](https://immunomart.com/wp-content/uploads/2024/03/HY-150596.gif)
Download Files:
CT1-3
SKU
HY-150596-Get quote
Category Reference compound
Tags Apoptosis;Bcl-2 Family;JNK, Apoptosis;MAPK/ERK Pathway, Cancer
Products Details
Product Description
– CT1-3 is a potent anticancer agent. CT1-3 induces mitochondria-mediated apoptosis by regulating JNK/Bcl-2/Bax/XIAP pathway. CT1-3 suppresses the epithelial mesenchymal transition (EMT) potential of human cancer cells (HCCs) via regulating the E-cadherin/Snail axis, thus inhibits tumorigenesis. CT1-3 has a strong antitumor effect in mice model and exhibits no significant hepatic and renal toxicity[1].
Web ID
– HY-150596
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C25H29NO3S2
References
– [1]Tao C, et al. CT1-3, a novel magnolol-sulforaphane hybrid suppresses tumorigenesis through inducing mitochondria-mediated apoptosis and inhibiting epithelial mesenchymal transition. Eur J Med Chem. 2020 Aug 1;199:112441.
CAS Number
– 2460738-32-1
Molecular Weight
– 455.63
SMILES
– OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=CC=C2OCCS(CCCCN=C=S)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Bcl-2 Family;JNK
Pathway
– Apoptosis;MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.