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Products Details
Product Description
– cSPM (Cyclic spermine) is a Aβ42 inhibitor. cSPM could suppress the aggregation of three different peptides, Aβ42, amylin and insulin, and decreases cytotoxicity[1].
Web ID
– HY-144752
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C27H57N7
References
– [1]Kunitomi R, et, al. Inhibition of amyloid formation of amyloid β (1-42), amylin and insulin by 1,5-diazacyclooctanes, a spermine-acrolein conjugate. Bioorg Med Chem. 2021 Sep 15;46:116391.
Molecular Weight
– 479.79
SMILES
– CCCCNCCCCN1CCCN2CCC3N(CCCN3CCC12)CCCCNCCCN
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
