Download Files:
Products Details
Product Description
– CSF1R-IN-17 (compound 9) is a potent and selective CSF1R antagonist, with an IC50 of 0.2 nM. CSF1R-IN-17 can inhibit osteoclast differentiation[1].
Web ID
– HY-155550
Shipping
– Room temperature
Molecular Formula
– C20H25N5O2
References
– [1]Aarhus TI, et, al. A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation. Eur J Med Chem. 2023 Jul 5;255:115344.
Molecular Weight
– 367.44
SMILES
– OCCC1=CC=C(C2=NC3=C(N(C)CC4CCOCC4)N=CN=C3N2)C=C1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– c-Fms
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
