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Products Details
Product Description
– CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1)[1].
Web ID
– HY-147617
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C23H22F3N5O
References
– [1]Wenyuan Qian, et al. Heterocyclic compound as csf-1r inhibitor and use thereof. Patent WO2019134662A1.
CAS Number
– 2361378-89-2
Molecular Weight
– 441.45
SMILES
– CC1=CC(NCC2=CN=C(C=C2)C(F)(F)F)=NC=C1C3=C4CNC(C4=C(C=C3)N(C)C)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– c-Fms
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
