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Products Details
Product Description
– CRS3123 is a potent and orally active narrow-spectrum antibiotic. CRS3123 inhibits bacterial methionyl-tRNA synthetase. CRS3123 has potent activity against Clostridium difficile (C. difficile) and aerobic Gram-positive bacteria but little activity against Gram-negative bacteria, including anaerobes. CRS3123 has the potential for the research of C. difficile infections[1].
Web ID
– HY-18324
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C19H19Br2N3O2S
References
– [1]Lomeli BK, et al. Multiple-Ascending-Dose Phase 1 Clinical Study of the Safety, Tolerability, and Pharmacokinetics of CRS3123, a Narrow-Spectrum Agent with Minimal Disruption of Normal Gut Microbiota. Antimicrob Agents Chemother. 2019; 64(1):e01395-19.
CAS Number
– 1013915-71-3
Molecular Weight
– 513.25
SMILES
– BrC1=C(OCC2)C([C@@H]2NCCCNC3=CC(C(SC=C4)=C4N3)=O)=CC(Br)=C1
Clinical Information
– Phase 2
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
