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Products Details
Product Description
– CREB-IN-1 TFA is a potent, orally active CREB inhibitor (IC50=0.18 µM). CREB-IN-1 TFA inhibits breast cancer cell growth[1].
Web ID
– HY-144318
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C35H32ClF3N3O10P
References
– [1]Peng J, et al. Design, Synthesis and Biological Evaluation of Prodrugs of 666-15 as Inhibitors of CREB-Mediated Gene Transcription. ACS Med Chem Lett. 2022; 13(3):388-395.
CAS Number
– 2912285-84-6
Molecular Weight
– 778.06
SMILES
– NCCCOC1=C(C=C2C=CC=CC2=C1)C(NCCOC3=CC4=CC=CC=C4C=C3C(NC5=CC=C(C=C5OP(O)(O)=O)Cl)=O)=O.OC(C(F)(F)F)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Pathway
– Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
