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CPUY201112
SKU
HY-111524-Get quote
Category Reference compound
Tags Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Apoptosis;HSP, Cancer
Products Details
Product Description
– CPUY201112 is a potent heat shock protein Hsp90 inhibitor with Kd of 27 nM. CPUY201112 induces p53-mediated apoptosis in MCF-7 cells, resulting in cell cycle arrest, which can be used in cancer research[1].
Web ID
– HY-111524
Shipping
– Room temperature
Molecular Formula
– C19H23N3O4
References
– [1]Xiao-Li X, et al. CPUY201112, a novel synthetic small-molecule compound and inhibitor of heat shock protein Hsp90, induces p53-mediated apoptosis in MCF-7 cells. Sci Rep. 2016 Jan 8;6:19004.Â
CAS Number
– 1860793-58-3
Molecular Weight
– 357.40
SMILES
– O=C(N1CCC2=NC(OCC)=NC=C2C1)C3=CC(C(C)C)=C(C=C3O)O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;HSP
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.