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CPPG
SKU
HY-101333-1 mg
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, mGluR, Neurological Disease
$150 – $460
Products Details
Product Description
– CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1].
Web ID
– HY-101333
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C11H14NO5P
References
– [1]Toms NJ, et al. The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist. Br J Pharmacol. 1996 Nov;119(5):851-4.
CAS Number
– 183364-82-1
Molecular Weight
– 271.21
Compound Purity
– 98.0
SMILES
– O=C(O)C(C1CC1)(N)C2=CC=C(P(O)(O)=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Target
– mGluR
Isoform
– mGluR
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.