CPPG

$150$460

Products Details

Product Description

– CPPG ((RS)-CPPG) is a potent group II/III mGlu receptors antagonist. CPPG exhibits some selectivity (approximately 20 fold) for group III (IC50=2.2 nM) over group II (IC50=46.2 nM) mGlu receptors in the rat cerebral cortex. CPPG has weak effects at group I mGlu receptors[1].

Web ID

– HY-101333

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C11H14NO5P

References

– [1]Toms NJ, et al. The effects of (RS)-alpha-cyclopropyl-4-phosphonophenylglycine ((RS)-CPPG), a potent and selective metabotropic glutamate receptor antagonist. Br J Pharmacol. 1996 Nov;119(5):851-4.

CAS Number

– 183364-82-1

Molecular Weight

– 271.21

Compound Purity

– 98.0

SMILES

– O=C(O)C(C1CC1)(N)C2=CC=C(P(O)(O)=O)C=C2

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Target

– mGluR

Isoform

– mGluR

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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