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CpG ODN 10101
$620 – $1,980
Products Details
Product Description
– CpG ODN 10101, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2(VQLRIRVAVIRA-NH2). CpG ODN 10101 induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 has antiviral and immunomodulatory properties that can influence chronic infection with HCV[1][2].
Web ID
– HY-150217
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-anti-virus
Molecular Formula
– N/A
References
– [1]Jason Kindrachuk, et al. A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity. Vaccine. 2009 Jul 23;27(34):4662-71.|[2]John G McHutchison, et al. Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus. Hepatology. 2007 Nov;46(5):1341-9.
CAS Number
– 1234402-77-7
Molecular Weight
– 6702.37
Compound Purity
– 94.06
SMILES
– [CpG ODN 10101]
Clinical Information
– No Development Reported
Research Area
– Infection; Inflammation/Immunology
Solubility
– H2O : ≥ 25 mg/mL
Target
– HCV;Toll-like Receptor (TLR)
Isoform
– TLR9
Pathway
– Anti-infection;Immunology/Inflammation
Product type
– Oligonucleotides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
