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CP-809101 (hydrochloride)
$94 – $634
Products Details
Product Description
– CP-809101 hydrochloride is a potent and highly selective 5-HT2C receptor agonist, with pEC50s of 9.96, 7.19 and 6.81 M for human 5HT2C, 5HT2B and 5HT2A receptor. CP-809101 hydrochloride inhibits conditioned avoidance responding in rats and antagonizes both PCP (phencyclidine hydrochloride)- and d-amphetamine-induced hyperactivity. CP-809101 hydrochloride also reduces food and nicotine dependence in rats, can be used in studies of antipsychotic and nicotine dependence[1][2].
Web ID
– HY-15543A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H18Cl2N4O
References
– [1]Siuciak JA, et al. CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity. Neuropharmacology. 2007 Feb;52(2):279-90. |[2]Higgins GA, et al. Evaluation of chemically diverse 5-HTâ‚‚c receptor agonists on behaviours motivated by food and nicotine and on side effect profiles. Psychopharmacology (Berl). 2013 Apr;226(3):475-90.
CAS Number
– 1215721-40-6
Molecular Weight
– 341.24
Compound Purity
– 99.37
SMILES
– [H]Cl.ClC1=CC(COC2=NC(N3CCNCC3)=CN=C2)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– H2O : 20 mg/mL (ultrasonic)
Target
– 5-HT Receptor
Isoform
– 5-HT2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
