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Products Details
Product Description
– COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC50 of 0.4 μM[1][2].
Web ID
– HY-105304
Shipping
– Room temperature
Molecular Formula
– C17H22O5S
References
– [1]Lushi Tan, et al. Practical enantioselective synthesis of a COX-2 specific inhibitor. Tetrahedron
Volume 58, Issue 37, 9 September 2002, Pages 7403-7410.|[2]Yves Leblanc, et al. Discovery of a potent and selective COX-2 inhibitor in the alkoxy lactone series with optimized metabolic profile. Bioorg Med Chem Lett. 2002 Nov 18;12(22):3317-20.
CAS Number
– 189954-93-6
Molecular Weight
– 338.42
SMILES
– CC(C)OC1=C(C2=CC=C(C=C2)S(C)(=O)=O)[C@@](C)(OC1=O)CC
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
