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Products Details
Product Description
– COX-2-IN-21 (Compound 5c) is a selective and orally active COX-2 inhibitor with an IC50 of 0.039 μM. COX-2-IN-21 shows promising anti-inflammatory potential[1].
Web ID
– HY-147815
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H22N6O4
References
– [1]Labib MB, et al. Novel tetrazole-based selective COX-2 inhibitors: Design, synthesis, anti-inflammatory activity, evaluation of PGE2, TNF-α, IL-6 and histopathological study. Bioorg Chem. 2020 Nov;104:104308.
CAS Number
– 2519631-11-7
Molecular Weight
– 422.44
SMILES
– CC(N1N=C(C2=CC=CC(N3N=NN=C3)=C2)CC1C4=CC(OC)=C(OC)C(OC)=C4)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX
Isoform
– COX-1;COX-2
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
