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Products Details
Product Description
– COX-2/15-LOX-IN-2 is a potent dual COX-2 and 15-LOX inhibitor with IC50 values of 0.065?μM and 1.86?μM, respectively. COX-2/15-LOX-IN-2 has potent antioxidant activity[1].
Web ID
– HY-155159
Shipping
– Room temperature
Molecular Formula
– C27H26N6OS2
References
– [1]Sara Elsayed, et al. Magic shotgun approach to anti-inflammatory pharmacotherapy: Synthesis of novel thienopyrimidine monomers/heterodimer as dual COX-2 and 15-LOX inhibitors endowed with potent antioxidant activity . Eur J Med Chem. 2023 Nov 15;260:115724.
Molecular Weight
– 514.66
SMILES
– COC(C=C1)=CC=C1C2=NC3=C(C(CCCC4)=C4S3)C(NNC5=C(C(CCCC6)=C6S7)C7=NC=N5)=N2
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX;Lipoxygenase
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
