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Products Details
Product Description
– COX-1/2-IN-5 (compound 2a) is a dual inhibitor of COX1/2 (IC50=2.650 μM, 0.958 μM), with anticancer activity. COX-1/2-IN-5 inhibits liver cancer HepG2 with an IC50 of 60.75 μM[1].
Web ID
– HY-155768
Shipping
– Room temperature
Molecular Formula
– C21H22N2O5S
References
– [1]Hawash M, et al. New Thiazole Carboxamide Derivatives as COX Inhibitors: Design, Synthesis, Anticancer Screening, In Silico Molecular Docking, and ADME Profile Studies. ACS Omega. 2023 Aug 6;8(32):29512-29526.
Molecular Weight
– 414.47
SMILES
– O=C(C1=C(C)N=C(C2=CC=CC(OC)=C2)S1)NC3=CC(OC)=C(OC)C(OC)=C3
Clinical Information
– No Development Reported
Research Area
– cancer
Solubility
– 10 mM in DMSO
Target
– COX
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
