Products Details

Product Description

– COX-1/2-IN-3 (Compound 7a) is a COX-1 and COX-2 inhibitor. COX-2-IN-15 shows anti-inflammatory activity with low toxicity[1].

Web ID

– HY-147693

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C14H8N2O8

References

– [1]Gonçalves DS, et al. Synthesis of novel 3,5,6-trisubstituted 2-pyridone derivatives and evaluation for their anti-inflammatory activity. Bioorg Med Chem. 2020 Jun 15;28(12):115549.

CAS Number

– 2428387-82-8

Molecular Weight

– 332.22

SMILES

– O=C1NC(C(O)=O)=C(C(C2=CC=C(C=C2)[N+]([O-])=O)=O)C=C1C(O)=O

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– COX

Isoform

– COX-1;COX-2

Pathway

– Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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