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Coumarin-SAHA
$84
Only 1000 item(s) left in stock.
Products Details
Product Description
– Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes[1].
Web ID
– HY-126829
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H22N2O5
References
– [1]Raushan K Singh, et al. Coumarin-suberoylanilide hydroxamic acid as a fluorescent probe for determining binding affinities and off-rates of histone deacetylase inhibitors. Anal Biochem
CAS Number
– 1260635-77-5
Molecular Weight
– 346.38
SMILES
– O=C(NO)CCCCCCC(NC1=CC=C(C(O2)=C1)C(C)=CC2=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– HDAC
Isoform
– HDAC8
Pathway
– Cell Cycle/DNA Damage;Epigenetics
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
