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Contezolid acefosamil (sodium)
$920 – $4,850
Products Details
Product Description
– Contezolid acefosamil sodium (MRX-4), a new and orally active oxazolidinone, is an antibiotic in study for complicated skin and soft tissue infections (cSSTI) caused by resistant Gram-positive bacteria. Contezolid acefosamil sodium (MRX-4) markedly reduces potential for myelosuppression and monoamine oxidase inhibition (MAOI)[1][2].
Web ID
– HY-19915B
Storage Temperature
– -80°C, stored under nitrogen
Shipping
– Dry Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H17F3N4NaO8P
References
– [1]Junzhen Wu, et al. Evaluation of the Effect of Contezolid (MRX-I) on the Corrected QT Interval in a Randomized, Double-Blind, Placebo- and Positive-Controlled Crossover Study in Healthy Chinese Volunteers. Antimicrob Agents Chemother. 2020 May 21;64(6):e02158-19.|[2]Mikhail F Gordeev, et al. New potent antibacterial oxazolidinone (MRX-I) with an improved class safety profile. J Med Chem. 2014 Jun 12;57(11):4487-97.|[3]Carolyn Shoen, et al. In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00493-18.
CAS Number
– 1807365-35-0
Molecular Weight
– 552.33
Compound Purity
– 99.38
SMILES
– FC(C(F)=C1N(C=C2)CCC2=O)=C(N(C(O3)=O)C[C@@H]3CN(C4=NOC=C4)[P](OC(C)=O)(O[Na])=O)C=C1F
Clinical Information
– Phase 3
Research Area
– Infection; Inflammation/Immunology
Solubility
– DMSO : 180 mg/mL (ultrasonic)
Target
– Antibiotic;Bacterial;Monoamine Oxidase
Isoform
– Oxazolidinone
Pathway
– Anti-infection;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
