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Compound 401
SKU
HY-19341-1 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;PI3K/Akt/mTOR, DNA-PK
$44 – $790
Products Details
Product Description
– Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro.
Web ID
– HY-19341
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H15N3O2
References
– [1]Ballou LM, et al. Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one. J Biol Chem. 2007 Aug 17;282(33):24463-70.
CAS Number
– 168425-64-7
Molecular Weight
– 281.31
Compound Purity
– 99.09
SMILES
– O=C1C=C(N2CCOCC2)N=C3N1C=CC4=C3C=CC=C4
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 10 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– DNA-PK
Pathway
– Cell Cycle/DNA Damage;PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.