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Products Details
Product Description
– Complement C1s-IN-1 is a potent, selective, orally active and cross the blood-brain barrier C1s inhibitor with an IC50 value of 36 nM[1].
Web ID
– HY-149278
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H20F2N6O
References
– [1]Ikeda Z, et al. Discovery of a Novel Series of Potent, Selective, Orally Available, and Brain-Penetrable C1s Inhibitors for Modulation of the Complement Pathway. J Med Chem. 2023 Apr 25.
Molecular Weight
– 422.43
SMILES
– NC1=C(C(F)=CC(N2C[C@H](C3=NOC(C)=C3)N(C4=CC(F)=CC=C4)CC2)=C5)C5=CN=N1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Complement System
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
