Columbianadin

$34$384

Products Details

Product Description

– Columbianadin, a natural coumarin from Heracleum hemsleyanum, is known to have various biological activities including anti-inflammatory and anti-cancer effects.

Web ID

– HY-N0362

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C19H20O5

References

– [1]Kang JI, et al. Columbianadin Inhibits Cell Proliferation by Inducing Apoptosis and Necroptosis in HCT116 Colon Cancer Cells. Biomol Ther (Seoul). 2016 May 1;24(3):320-7.|[2]Zhang YB, et al. Tissue distribution study of columbianadin and its active metabolite columbianetin in rats. Biomed Chromatogr. 2016 Feb;30(2):256-62.

CAS Number

– 5058-13-9

Molecular Weight

– 328.36

Compound Purity

– 99.95

SMILES

– C/C=C(C)C(OC(C)([C@@H]1CC2=C(O3)C(C=CC3=O)=CC=C2O1)C)=O

Clinical Information

– No Development Reported

Research Area

– Cancer; Inflammation/Immunology

Solubility

– DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Apoptosis

Pathway

– Apoptosis

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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