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Colistin adjuvant-1

Products Details

Product Description

– Colistin adjuvant-1 is a colistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibits NF-κB with an IC50 of 0.209 μM[1].

Web ID

– HY-145439

Shipping

– Room temperature

Molecular Formula

– C16H7F9N2O

References

– [1]Li H, et al. Benzimidazole Isosteres of Salicylanilides Are Highly Active Colistin Adjuvants. ACS Infect Dis. 2021 Nov 9.

CAS Number

– 2862800-15-3

Molecular Weight

– 414.23

SMILES

– OC(C=C(C(F)(F)F)C=C1)=C1C2=NC3=C(C(F)(F)F)C=C(C(F)(F)F)C=C3N2

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Bacterial;NF-κB

Pathway

– Anti-infection;NF-κB

Product type

– Reference compound

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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